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Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor., Blom AEM, Campello HR, Lester HA, Gallagher T, Dougherty DA., J Am Chem Soc. October 9, 2019; 141 (40): 15840-15849.


Prognostic significance of TPX2 and NIBP in esophageal cancer., Sui C, Song Z, Yu H, Wang H., Oncol Lett. October 1, 2019; 18 (4): 4221-4229.      


Polymer effects modulate binding affinities in disordered proteins., Vancraenenbroeck R, Harel YS, Zheng W, Hofmann H., Proc Natl Acad Sci U S A. September 24, 2019; 116 (39): 19506-19512.          


Phosphorylation dependent α-synuclein degradation monitored by in-cell NMR., Zheng W, Zhang Z, Ye Y, Wu Q, Liu M, Li C., Chem Commun (Camb). September 17, 2019; 55 (75): 11215-11218.


Pore-modulating toxins exploit inherent slow inactivation to block K+ channels., Karbat I, Altman-Gueta H, Fine S, Szanto T, Hamer-Rogotner S, Dym O, Frolow F, Gordon D, Panyi G, Gurevitz M, Reuveny E., Proc Natl Acad Sci U S A. September 10, 2019; 116 (37): 18700-18709.


Pharmacological characterization of a homomeric nicotinic acetylcholine receptor formed by Ancylostoma caninum ACR-16., Choudhary S, Tipton JG, Abongwa M, Brewer MT, Chelladurai JJ, Musselman N, Martin RJ, Robertson AP., Invert Neurosci. September 5, 2019; 19 (4): 11.


Polyamine biosynthesis in Xenopus laevis: the xlAZIN2/xlODC2 gene encodes a lysine/ornithine decarboxylase., Lambertos A, Peñafiel R., PLoS One. September 3, 2019; 14 (9): e0218500.                                


Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2., Khetchoumian K, Balsalobre A, Mayran A, Christian H, Chénard V, St-Pierre J, Drouin J., Nat Commun. September 3, 2019; 10 (1): 3960.                                  


PTK7 proteolytic fragment proteins function during early Xenopus development., Lichtig H, Cohen Y, Bin-Nun N, Golubkov V, Frank D., Dev Biol. September 1, 2019; 453 (1): 48-55.        


Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site., Watson ER, Grace CRR, Zhang W, Miller DJ, Davidson IF, Prabu JR, Yu S, Bolhuis DL, Kulko ET, Vollrath R, Haselbach D, Stark H, Peters JM, Brown NG, Sidhu SS, Schulman BA., Proc Natl Acad Sci U S A. August 27, 2019; 116 (35): 17280-17289.


Phosphomimetic substitution at Ser-33 of the chloroquine resistance transporter PfCRT reconstitutes drug responses in Plasmodium falciparum., Sanchez CP, Moliner Cubel S, Nyboer B, Jankowska-Döllken M, Schaeffer-Reiss C, Ayoub D, Planelles G, Lanzer M., J Biol Chem. August 23, 2019; 294 (34): 12766-12778.


Phosphatidylinositol 4,5-bisphosphate (PIP2) and Ca2+ are both required to open the Cl- channel TMEM16A., Tembo M, Wozniak KL, Bainbridge RE, Carlson AE., J Biol Chem. August 16, 2019; 294 (33): 12556-12564.


Phosphoinositides modulate the voltage dependence of two-pore channel 3., Shimomura T, Kubo Y., J Gen Physiol. August 5, 2019; 151 (8): 986-1006.                              


Positively charged amino acid residues in the extracellular loops A and C of lens aquaporin 0 interact with the negative charges in the plasma membrane to facilitate cell-to-cell adhesion., Kumari S, Taginik G, Varadaraj S, Varadaraj K., Exp Eye Res. August 1, 2019; 185 107682.              


Proline Residues in the Transmembrane/Extracellular Domain Interface Loops Have Different Behaviors in 5-HT3 and nACh Receptors., Mosesso R, Dougherty DA, Lummis SCR., ACS Chem Neurosci. July 17, 2019; 10 (7): 3327-3333.


PeIA-5466: A Novel Peptide Antagonist Containing Non-natural Amino Acids That Selectively Targets α3β2 Nicotinic Acetylcholine Receptors., Hone AJ, Fisher F, Christensen S, Gajewiak J, Larkin D, Whiteaker P, McIntosh JM., J Med Chem. July 11, 2019; 62 (13): 6262-6275.


Philanthotoxin Analogues That Selectively Inhibit Ganglionic Nicotinic Acetylcholine Receptors with Exceptional Potency., Kachel HS, Franzyk H, Mellor IR., J Med Chem. July 11, 2019; 62 (13): 6214-6222.


Plasticity for colour adaptation in vertebrates explained by the evolution of the genes pomc, pmch and pmchl., Bertolesi GE, Zhang JZ, McFarlane S., Pigment Cell Melanoma Res. July 1, 2019; 32 (4): 510-527.  


PDGF-B: The missing piece in the mosaic of PDGF family role in craniofacial development., Corsinovi D, Giannetti K, Cericola A, Naef V, Ori M., Dev Dyn. July 1, 2019; 248 (7): 603-612.            


Peroxisome protein import recapitulated in Xenopus egg extracts., Romano FB, Blok NB, Rapoport TA., J Cell Biol. June 3, 2019; 218 (6): 2021-2034.              


Pharmacological characterization of JWX-A0108 as a novel type I positive allosteric modulator of α7 nAChR that can reverse acoustic gating deficits in a mouse prepulse inhibition model., Sun LL, Yang TY, Wei NN, Lu W, Jiao WX, Zhou QQ, Miao YZ, Gao Q, Wang XT, Sun Q, Wang K., Acta Pharmacol Sin. June 1, 2019; 40 (6): 737-745.


Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes., Gnangnon B, Fréville A, Cailliau K, Leroy C, De Witte C, Tulasne D, Martoriarti A, Jung V, Guerrera IC, Marion S, Khalife J, Pierrot C., Sci Rep. May 31, 2019; 9 (1): 8120.  


Positively Charged Tags Impede Protein Mobility in Cells as Quantified by 19F NMR., Ye Y, Wu Q, Zheng W, Jiang B, Pielak GJ, Liu M, Li C., J Phys Chem B. May 30, 2019; 123 (21): 4527-4533.


Preserving Genome Integrity During the Early Embryonic DNA Replication Cycles., Kermi C, Aze A, Maiorano D., Genes (Basel). May 24, 2019; 10 (5):           


Peroxiredoxin5 Controls Vertebrate Ciliogenesis by Modulating Mitochondrial Reactive Oxygen Species., Ji Y, Chae S, Lee HK, Park I, Kim C, Ismail T, Kim Y, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Moon PG, Baek MC, Park MJ, Kil IS, Rhee SG, Kim J, Huh YH, Shin JY, Min KJ, Kwon TK, Jang DG, Woo HA, Kwon T, Park TJ, Lee HS., Antioxid Redox Signal. May 10, 2019; 30 (14): 1731-1745.  


PbrSLAH3 is a nitrate-selective anion channel which is modulated by calcium-dependent protein kinase 32 in pear., Chen G, Wang L, Chen Q, Qi K, Yin H, Cao P, Tang C, Wu X, Zhang S, Wang P, Wu J., BMC Plant Biol. May 8, 2019; 19 (1): 190.            


Pyrophosphate Stimulates the Phosphate-Sodium Symporter of Trypanosoma brucei Acidocalcisomes and Saccharomyces cerevisiae Vacuoles., Potapenko E, Cordeiro CD, Huang G, Docampo R., mSphere. April 3, 2019; 4 (2):           


Purification and characterization of a urea sensitive lactate dehydrogenase from skeletal muscle of the African clawed frog, Xenopus laevis., Childers CL, Storey KB., J Comp Physiol B. April 1, 2019; 189 (2): 271-281.


Protons Differentially Activate TDAG8 Homologs from Various Species., Musha S, Nagayama S, Murakami S, Kojima R, Deai M, Sato K, Okajima F, Ueharu H, Tomura H., Zoolog Sci. April 1, 2019; 36 (2): 105-111.


Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA., Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ., Cell Rep. March 26, 2019; 26 (13): 3522-3536.e5.                  


Paracetamol-induced liver injury modelled in Xenopus laevis embryos., Saide K, Sherwood V, Wheeler GN., Toxicol Lett. March 1, 2019; 302 83-91.            


Probing the Dynamics and Structural Topology of the Reconstituted Human KCNQ1 Voltage Sensor Domain (Q1-VSD) in Lipid Bilayers Using Electron Paramagnetic Resonance Spectroscopy., Dixit G, Sahu ID, Reynolds WD, Wadsworth TM, Harding BD, Jaycox CK, Dabney-Smith C, Sanders CR, Lorigan GA., Biochemistry. February 19, 2019; 58 (7): 965-973.


PCP-dependent transcellular regulation of actomyosin oscillation facilitates convergent extension of vertebrate tissue., Shindo A, Inoue Y, Kinoshita M, Wallingford JB., Dev Biol. February 15, 2019; 446 (2): 159-167.        


Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation., Zhu W, Mazzanti A, Voelker TL, Hou P, Moreno JD, Angsutararux P, Naegle KM, Priori SG, Silva JR., Circ Res. February 15, 2019; 124 (4): 539-552.


Peptides for Skin Protection and Healing in Amphibians., Demori I, Rashed ZE, Corradino V, Catalano A, Rovegno L, Queirolo L, Salvidio S, Biggi E, Zanotti-Russo M, Canesi L, Catenazzi A, Grasselli E., Molecules. January 18, 2019; 24 (2):       


Phosphatase 1 Nuclear Targeting Subunit (PNUTS) Regulates Aurora Kinases and Mitotic Progression., Wang F, Wang L, Fisher LA, Li C, Wang W, Peng A., Mol Cancer Res. January 1, 2019; 17 (1): 10-19.


Proteolytic Activation of Bmps: Analysis of Cleavage in Xenopus Oocytes and Embryos., Kim HS, McKnite A, Christian JL., Methods Mol Biol. January 1, 2019; 1891 115-133.


Pymetrozine activates TRPV channels of brown planthopper Nilaparvata lugens., Wang LX, Niu CD, Salgado VL, Lelito K, Stam L, Jia YL, Zhang Y, Gao CF, Wu SF., Pestic Biochem Physiol. January 1, 2019; 153 77-86.


PACAP-38 and PACAP(6-38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB3-Receptor., Pedersen SH, la Cour SH, Calloe K, Hauser F, Olesen J, Klaerke DA, Jansen-Olesen I., Front Cell Neurosci. January 1, 2019; 13 114.              


Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling., Wu KZL, Jones RA, Tachie-Menson T, Macartney TJ, Wood NT, Varghese J, Gourlay R, Soares RF, Smith JC, Sapkota GP., Wellcome Open Res. January 1, 2019; 4 133.          


Prominin-1 and Photoreceptor Cadherin Localization in Xenopus laevis: Protein-Protein Relationships and Function., Carr BJ, Yang LL, Moritz OL., Adv Exp Med Biol. January 1, 2019; 1185 483-487.


Protein and Chemical Determinants of BL-1249 Action and Selectivity for K2P Channels., Pope L, Arrigoni C, Lou H, Bryant C, Gallardo-Godoy A, Renslo AR, Minor DL., ACS Chem Neurosci. December 19, 2018; 9 (12): 3153-3165.


Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development., Kim Y, Jeong Y, Kwon K, Ismail T, Lee HK, Kim C, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Kwon T, Lee HS., Epigenetics Chromatin. December 6, 2018; 11 (1): 72.                


Palmitate Stimulates the Epithelial Sodium Channel by Elevating Intracellular Calcium, Reactive Oxygen Species, and Phosphoinositide 3-Kinase Activity., Wang QS, Liang C, Niu N, Yang X, Chen X, Song BL, Yu CJ, Wu MM, Zhang ZR, Ma HP., Oxid Med Cell Longev. December 2, 2018; 2018 7560610.                  


Probing the molecular basis for affinity/potency- and efficacy-based subtype-selectivity exhibited by benzodiazepine-site modulators at GABAA receptors., Söderhielm PC, Balle T, Bak-Nyhus S, Zhang M, Hansen KM, Ahring PK, Jensen AA., Biochem Pharmacol. December 1, 2018; 158 339-358.


Presenilin Regulates Retinotectal Synapse Formation through EphB2 Receptor Processing., Liu Z, Thakar A, Santoro SW, Pratt KG., Dev Neurobiol. December 1, 2018; 78 (12): 1171-1190.


Polystyrene microplastics did not affect body growth and swimming activity in Xenopus laevis tadpoles., De Felice B, Bacchetta R, Santo N, Tremolada P, Parolini M., Environ Sci Pollut Res Int. December 1, 2018; 25 (34): 34644-34651.


PLK4 is a microtubule-associated protein that self-assembles promoting de novo MTOC formation., Montenegro Gouveia S, Zitouni S, Kong D, Duarte P, Ferreira Gomes B, Sousa AL, Tranfield EM, Hyman A, Loncarek J, Bettencourt-Dias M., J Cell Sci. November 9, 2018; 132 (4):                 


Phthalates modulate steroid 5-reductase transcripts in the Western clawed frog embryo., Bissegger S, Pineda Castro MA, Yargeau V, Langlois VS., Comp Biochem Physiol C Toxicol Pharmacol. November 1, 2018; 213 39-46.


Prognostic and clinical value of Targeting protein for Xenopus kinesin-like protein 2 in patients with gastrointestinal tract cancers: A meta-analysis., Liu W, Xu J, Zhang C., Medicine (Baltimore). November 1, 2018; 97 (46): e13303.          

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